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Gout is a certain type of disease which is caused by the excess uric acid found in the blood and forms as urate crystals in the long run.

Safety of allopurinol compared with other urate-lowering drugs in patients with gout: a systematic review and meta-analysis.

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An increase in acute attacks of gout has been reported during the early stages of administration of Allopurinol, even when normal or subnormal serum uric acid levels have been attained.

Allopurinol cannot be used in patients with hypersensitivity to the medication, in individuals with a hepatic or renal disorders, primary hemochromatosis, asymptomatic hyperuricemia, acute gout, pregnancy, lactation.

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Miniature Schnauzers and Yorkshire Terriers do so as a result of their tendency to have portosystemic shunts, which are abnormal blood vessels that bypass the liver, predisposing dogs to urate stones.

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